Novascan Technologies glass and mica surfaces with defined chemistries are designed for use in:

• Atomic Force Microscopy (AFM)
• Confocal Microscopy
• TIRF (Total Internal Reflection Flourescence)
• Protein Binding Studies
• Chemical Binding Studies
• NSOM/SNOM (Nearfield Scanning Optical Microscopy)

Modified surfaces are comprised primarily of either thiol-based or silane-based self assembled monolayers (SAMs). Thiol modified surfaces, available with CH₃, COOH, OH and succinimde end groups, are attached via chemical apsorption to a freshly applied layer of gold. Alternatively, silane monolayers, including APTES, are tethered to oxide layers on the surface of either glass or mica substrates. Further modifications can yield a variety of surface chemistries including NH₃, maleimide, biotin, streptavidin, neutravidin, antibodies, PEG linkers and a number of other molecules.

Standard mica surfaces are 1cm x 1cm although custom sizing is available. Glass surfaces are 12mm round pieces, however other sizes may also be available. Be sure to mention custom requirements when inquiring. As is always the case at Novascan, we welcome the opportunity to discuss custom modifications including custom particle attachment or chemical modifications.

• Inter-molecular Force Measurement
• Chemical Sensing and Detection
• Hydrophilic/Hydrophobic Interaction
• Attractive/Repulsive Regimes
• Adhesion Forces
• Unbinding Forces
• Surface Mapping

SUR.MICA.AP - Amino Silanized (APTES) mica
SUR.MICA.OH - Au coated mica with an OH surface
SUR.MICA.CH3 - Au coated mica with a CH₃ surface
SUR.MICA.COOH - Au coated mica with COOH Surface
SUR.MICA.SUC - Au coated mica with a succinimide surface
SUR.MICA.PEG.BIO - Mica surface with Biotin terminated flexible PEG linker
SUR.MICA.PEG.NH3 - Mica surface with NH₃ terminated flexible PEG linker
SUR.MICA.PEG.MAL - Mica surface with Maleimide terminated flexible PEG linker
SUR.MICA.PEG.COOH - Mica surface with COOH terminated flexible PEG linker

SUR.GS.AP - Amino Silanized (APTES) Glass
SUR.GS.OH - Au coated glass with an OH Surface
SUR.GS.CH3 - Au coated glass with a CH₃ Surface
SUR.GS.COOH - Au coated glass with a COOH Surfaces
SUR.GS.SUC Succinimide Surfaces...
SUR.GS.PEG.BIO Surface with Biotin terminated flexible PEG linker
SUR.GS.PEG.NH3 Surface with NH₃ terminated flexible PEG linker
SUR.GS.PEG.MAL Surface with Maleimide terminated flexible PEG linker
SUR.GS.PEG.COOH Surface with COOH terminated flexible PEG linker